Ser303
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Home > Phosphorylation Site Page: > Ser303  -  TACSTD2 (human)

Site Information
VITNRRKsGKYKKVE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451171

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 2 )

Upstream Regulation
Kinases, in vitro:
PKCA (human) ( 3 )

Downstream Regulation
Effects of modification on TACSTD2:
protein conformation ( 2 )

References 

1

Guerra E, et al. (2022) Trop-2, Na/K ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion. Oncogene
35132180   Curated Info

2

Pavšič M, et al. (2015) The cytosolic tail of the tumor marker protein Trop2 - a structural switch triggered by phosphorylation. Sci Rep 5, 10324
25981199   Curated Info

3

Basu A, Goldenberg DM, Stein R (1995) The epithelial/carcinoma antigen EGP-1, recognized by monoclonal antibody RS7-3G11, is phosphorylated on serine 303. Int J Cancer 62, 472-9
7635574   Curated Info