Lys443

Site Information
THQPPQTkWyTPIkG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 12287459

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 2 ) , MV4-11 (macrophage) ( 2 ) , PC3 (prostate cell) ( 3 ) , U2OS (bone cell) ( 1 )

Upstream Regulation
Treatments:	MG132 ( 2 )

References
1	Povlsen LK, et al. (2012) Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Nat Cell Biol 14, 1089-98 23000965 Curated Info
2	Wagner SA, et al. (2011) A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles. Mol Cell Proteomics 10, M111.013284 21890473 Curated Info
3	Possemato A (2009) CST Curation Set: 8581; Year: 2010; Biosample/Treatment: cell line, PC3/control; Disease: prostate cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: Ub(K-e-GG) Curated Info