Lys508
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Home > Mono-methylation Site Page: > Lys508  -  PARP1 (human)

Site Information
AALskKSkGQVkEEG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 12261103
Available spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 )
Disease tissue studied:
breast cancer ( 4 , 5 , 6 , 7 ) , breast cancer, surrounding tissue ( 4 , 7 ) , lung cancer ( 2 , 3 ) , non-small cell lung cancer ( 2 , 3 ) , non-small cell lung adenocarcinoma ( 3 )
Relevant cell line - cell type - tissue:

References 

1

Kassner I, et al. (2013) SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress. Open Biol 3, 120173
24088713   Curated Info

2

Rikova K (2013) CST Curation Set: 20129; Year: 2013; Biosample/Treatment: cell line, H1650, HCC827, H1975, Calu-3, H2106; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1K
Curated Info

3

Rikova K (2013) CST Curation Set: 20132; Year: 2013; Biosample/Treatment: cell line, H1666, CAL-12T, H2405, HCC44, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1K
Curated Info

4

Tucker M (2010) CST Curation Set: 9906; Year: 2010; Biosample/Treatment: tissue, breast/untreated; Disease: breast cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1K
Curated Info

5

Tucker M (2010) CST Curation Set: 9905; Year: 2010; Biosample/Treatment: tissue, breast/untreated; Disease: breast cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1K
Curated Info

6

Tucker M (2010) CST Curation Set: 9904; Year: 2010; Biosample/Treatment: tissue, breast/untreated; Disease: breast cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1K
Curated Info

7

Tucker M (2010) CST Curation Set: 9907; Year: 2010; Biosample/Treatment: tissue, breast/untreated; Disease: breast cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1K
Curated Info

8

Possemato A (2009) CST Curation Set: 8355; Year: 2009; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1K
Curated Info

9

Possemato A (2009) CST Curation Set: 8354; Year: 2009; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1K
Curated Info