Tyr547
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Home > Phosphorylation Site Page: > Tyr547  -  Fe65 (mouse)

Site Information
VQKFQVYyLGNVPVA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451143

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
CHO (fibroblast) [EphB1 (human), transfection] ( 1 ) , COS (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Abl (mouse) ( 1 )
Kinases, in vitro:
Abl (mouse) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Perkinton MS, et al. (2004) The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling. J Biol Chem 279, 22084-91
15031292   Curated Info

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