Ser13
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser13  -  DAT (rat)

Site Information
CsVGPMssVVAPAKE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451138

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 1 , 3 ) , [32P] ATP in vitro ( 1 ) , [32P] bio-synthetic labeling ( 2 , 3 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 3 ) , phosphoamino acid analysis ( 3 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
'brain, striatum' ( 1 , 3 ) , COS (fibroblast) ( 2 ) , LLC-PK1 (renal) ( 1 , 2 )

Upstream Regulation
Kinases, in vitro:
CAMK2A (human) ( 1 ) , PKCA (human) ( 1 )
Treatments:
OAG ( 3 ) , okadaic_acid ( 3 ) , phorbol_ester ( 1 ) , U0126 ( 2 )

References 

1

Moritz AE, et al. (2013) Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding. J Biol Chem 288, 20-32
23161550   Curated Info

2

Lin Z, et al. (2003) Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites. J Biol Chem 278, 20162-70
12660249   Curated Info

3

Foster JD, Pananusorn B, Vaughan RA (2002) Dopamine transporters are phosphorylated on N-terminal serines in rat striatum. J Biol Chem 277, 25178-86
11994276   Curated Info