Ser12

Site Information
KCsVGPMssVVAPAK SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 451137

In vivo Characterization
Methods used to characterize site in vivo:	2D analysis ( 3 ) , [32P] bio-synthetic labeling ( 2 , 3 ) , mutation of modification site ( 2 ) , phospho-antibody ( 3 ) , phosphoamino acid analysis ( 3 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:	'brain, striatum' ( 3 ) , COS (fibroblast) ( 2 ) , LLC-PK1 (renal) ( 2 )

Upstream Regulation
Treatments:	OAG ( 3 ) , okadaic_acid ( 3 ) , U0126 ( 2 )

References
1	Moritz AE, et al. (2013) Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding. J Biol Chem 288, 20-32 23161550 Curated Info
2	Lin Z, et al. (2003) Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites. J Biol Chem 278, 20162-70 12660249 Curated Info
3	Foster JD, Pananusorn B, Vaughan RA (2002) Dopamine transporters are phosphorylated on N-terminal serines in rat striatum. J Biol Chem 277, 25178-86 11994276 Curated Info