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Powered by Cell Signaling Technology |
| Site Information |
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| PkRHtVLyIsPPPED SwissProt Entrez-Gene |
| Blast this site against: NCBI SwissProt PDB |
| Site Group ID: 12127405 |
| In vivo Characterization | |
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| Methods used to characterize site in vivo: | |
| Relevant cell line - cell type - tissue: | |
| Upstream Regulation | |
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| Putative in vivo kinases: | |
| Putative upstream phosphatases: | |
| Phosphatases, in vitro: | |
| Treatments: | |
| Downstream Regulation | |
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| Effects of modification on NFAT5: | |
| Effects of modification on biological processes: | |
| Induce interaction with: | |
| References | |
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Zappe M, et al. (2018) NFAT5 Isoform C Controls Biomechanical Stress Responses of Vascular Smooth Muscle Cells. Front Physiol 9, 1190
30190682 Curated Info |
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Gallazzini M, et al. (2010) c-Abl mediates high NaCl-induced phosphorylation and activation of the transcription factor TonEBP/OREBP. FASEB J 24, 4325-35
20585028 Curated Info |
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Zhou X, Gallazzini M, Burg MB, Ferraris JD (2010) Contribution of SHP-1 protein tyrosine phosphatase to osmotic regulation of the transcription factor TonEBP/OREBP. Proc Natl Acad Sci U S A 107, 7072-7
20351292 Curated Info |
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Irarrazabal CE, et al. (2010) Phospholipase C-gamma1 is involved in signaling the activation by high NaCl of the osmoprotective transcription factor TonEBP/OREBP. Proc Natl Acad Sci U S A 107, 906-11
20080774 Curated Info |
