|
Powered by Cell Signaling Technology |
Site Information |
---|
SPLTTGVyVKMPPTE SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 450897 |
In vivo Characterization | |
---|---|
Methods used to characterize site in vivo: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
---|---|
Regulatory protein: | |
Treatments: |
Downstream Regulation | |
---|---|
Effects of modification on CTLA-4: | |
Induce interaction with: |
References | |
---|---|
Guntermann C, Alexander DR (2002) CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases. J Immunol 168, 4420-9
11970985 Curated Info |
|
Baroja ML, et al. (2000) The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation. J Immunol 164, 49-55
10604992 Curated Info |