Ser305
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Home > Phosphorylation Site Page: > Ser305  -  PLK4 (mouse)

Site Information
sGtsLsGsLLDRRLL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 12122401

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 2 ) , mutation of modification site ( 2 )
Disease tissue studied:
colorectal cancer ( 2 ) , colorectal carcinoma ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PLK4 (mouse) ( 2 )

Downstream Regulation
Effects of modification on PLK4:
intracellular localization ( 1 ) , protein degradation ( 2 ) , ubiquitination ( 2 )

References 

1

Rosario CO, et al. (2015) A novel role for Plk4 in regulating cell spreading and motility. Oncogene 34, 3441-51
25174401   Curated Info

2

Holland AJ, et al. (2010) Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability. J Cell Biol 188, 191-8
20100909   Curated Info