Lys1024
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Home > Sumoylation Site Page: > Lys1024  -  p300 (human)

Site Information
TELkTEIkEEEDQPS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 12063901

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , immunoprecipitation ( 2 ) , modification-specific antibody ( 2 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Disease tissue studied:
bone cancer ( 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on p300:
molecular association, regulation ( 2 )
Effects of modification on biological processes:
transcription, inhibited ( 2 )
Induce interaction with:
HDAC6 (human) ( 2 )

References 

1

Lumpkin RJ, et al. (2017) Site-specific identification and quantitation of endogenous SUMO modifications under native conditions. Nat Commun 8, 1171
29079793   Curated Info

2

Girdwood D, et al. (2003) P300 transcriptional repression is mediated by SUMO modification. Mol Cell 11, 1043-54
12718889   Curated Info