Ser434

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Home > Phosphorylation Site Page: > Ser434 - CLOCK (human)

Site Information
sPtPsASsRSsRKSS SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 12059703

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 )

Upstream Regulation
Regulatory protein:	BMAL1 (human) ( 1 )

Downstream Regulation
Effects of modification on CLOCK:	protein degradation ( 1 )

References
1	Spengler ML, Kuropatwinski KK, Schumer M, Antoch MP (2009) A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation. Cell Cycle 8, 4138-46 19946213 Curated Info

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