Ser126
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Home > Phosphorylation Site Page: > Ser126  -  PXN (rat)

Site Information
SFPNKQKsAEPsPtV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450227

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , phospho-antibody ( 2 )
Relevant cell line - cell type - tissue:
adipose tissue ( 1 ) , heart ( 1 ) , intestine ( 1 ) , kidney ( 1 ) , liver ( 1 ) , lung ( 1 ) , PC-12 (chromaffin) ( 2 ) , spleen ( 1 ) , stomach ( 1 ) , testis ( 1 ) , thymus ( 1 )

Upstream Regulation
Putative in vivo kinases:
GSK3A (rat) ( 2 ) , GSK3B (rat) ( 2 )
Treatments:
lithium ( 2 ) , NGF ( 2 ) , U0126 ( 2 )

Downstream Regulation
Effects of modification on PXN:
intracellular localization ( 2 )

References 

1

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info

2

Cai X, Li M, Vrana J, Schaller MD (2006) Glycogen synthase kinase 3- and extracellular signal-regulated kinase-dependent phosphorylation of paxillin regulates cytoskeletal rearrangement. Mol Cell Biol 26, 2857-68
16537926   Curated Info

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