Ser8
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Home > Phosphorylation Site Page: > Ser8  -  Kv3.4 (human)

Site Information
MISSVCVssYRGRKs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451075

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 ) , oocyte [CPEB (mouse)] ( 2 )

Upstream Regulation
Kinases, in vitro:
PKCA (rat) ( 2 ) , PKCB (human) ( 2 ) , PKCG (human) ( 2 )
Treatments:
MLN8054 ( 1 )

Downstream Regulation
Effects of modification on Kv3.4:
receptor inactivation, altered ( 2 )

References 

1

Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546   Curated Info

2

Beck EJ, Sorensen RG, Slater SJ, Covarrubias M (1998) Interactions between multiple phosphorylation sites in the inactivation particle of a K+ channel. Insights into the molecular mechanism of protein kinase C action. J Gen Physiol 112, 71-84
9649584   Curated Info

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