Lys121
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Home > Sumoylation Site Page: > Lys121  -  C/EBP-epsilon (human)

Site Information
DPRAVAVkEEPRGPE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 12004436

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , mutation of modification site ( 1 , 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 , 2 )

Downstream Regulation
Effects of modification on C/EBP-epsilon:
activity, induced ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 , 2 )

References 

1

Kim J, et al. (2005) Repression and coactivation of CCAAT/enhancer-binding protein epsilon by sumoylation and protein inhibitor of activated STATx proteins. J Biol Chem 280, 12246-54
15661739   Curated Info

2

Kim J, et al. (2002) Transcriptional activity of CCAAT/enhancer-binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylation. J Biol Chem 277, 38037-44
12161447   Curated Info

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