Tyr497
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Home > Phosphorylation Site Page: > Tyr497  -  IL4R (human)

Site Information
VIAGNPAyRSFSNSL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451065

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
IL-4 ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Zamorano J, Keegan AD (1998) Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. J Immunol 161, 859-67
9670964   Curated Info