Ser347
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Home > Phosphorylation Site Page: > Ser347  -  CASP8 (human)

Site Information
FTGLkCPsLAGkPkV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450983

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , immunoprecipitation ( 1 ) , phosphopeptide mapping ( 1 )
Relevant cell line - cell type - tissue:
neutrophil ( 1 )

Upstream Regulation
Putative in vivo kinases:
P38A (human) ( 1 )
Kinases, in vitro:
P38A (human) ( 1 )

Downstream Regulation
Effects of modification on CASP8:
activity, inhibited ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Alvarado-Kristensson M, et al. (2004) p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils. J Exp Med 199, 449-58
14970175   Curated Info