Ser299
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Home > Phosphorylation Site Page: > Ser299  -  TNF-R1 (mouse)

Site Information
PVSStPIsPIFGPSN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450967

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , mutation of modification site ( 2 ) , phosphoamino acid analysis ( 2 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 2 ) , macrophage-bone marrow ( 2 )

Upstream Regulation
Putative in vivo kinases:
ERK2 (mouse) ( 2 )
Kinases, in vitro:
ERK2 (human) ( 1 ) , ERK2 (mouse) ( 2 )
Treatments:
TNF ( 2 )

References 

1

Van Linden AA, Cottin V, Frankel SK, Riches DW (2005) Hierarchical phosphorylation of the TNF-alpha receptor, TNF-R1, by p42Mapk/Erk at basic Pro-directed kinase sites. Biochemistry 44, 6980-9
15865443   Curated Info

2

Van Linden AA, Cottin V, Leu C, Riches DW (2000) Phosphorylation of the membrane proximal region of tumor necrosis factor receptor CD120a (p55) at ERK consensus sites. J Biol Chem 275, 6996-7003
10702263   Curated Info