Ser388

Site Information
RRNELKRsFFALRDQ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 450961

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 1 , 2 )
Relevant cell line - cell type - tissue:	3T3 (fibroblast) ( 2 ) , HEK293T (epithelial) ( 2 ) , keratinocyte-skin ( 1 )

Downstream Regulation
Effects of modification on Myc:	activity, inhibited ( 1 , 2 ) , molecular association, regulation ( 2 )
Effects of modification on biological processes:	apoptosis, inhibited ( 2 ) , cell cycle regulation ( 2 ) , cell growth, altered ( 2 ) , transcription, altered ( 1 ) , transcription, inhibited ( 2 )
Inhibit interaction with:	MAX (mouse) ( 2 )

References
1	Berta MA, Baker CM, Cottle DL, Watt FM (2010) Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation. EMBO Mol Med 2, 16-25 20043278 Curated Info
2	Huang Z, Traugh JA, Bishop JM (2004) Negative control of the Myc protein by the stress-responsive kinase Pak2. Mol Cell Biol 24, 1582-94 14749374 Curated Info