Ser246
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Home > Phosphorylation Site Page: > Ser246  -  NFkB-p105 (mouse)

Site Information
DsKAPNAsNLKIVRM   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1170753400

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
E.coli (bacterial) ( 1 )

Upstream Regulation
Kinases, in vitro:
Chk1 (human) ( 1 )

Downstream Regulation
Effects of modification on NFkB-p105:
molecular association, regulation ( 1 ) , protein conformation ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )
Inhibit interaction with:
DNA ( 1 )

References 

1

Vonderach M, et al. (2018) DNA Binding and Phosphorylation Regulate the Core Structure of the NF-κB p50 Transcription Factor. J Am Soc Mass Spectrom
29873020   Curated Info