Thr180
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Home > Phosphorylation Site Page: > Thr180  -  Kir6.2 (human)

Site Information
QAHRRAEtLIFSKHA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450652

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , myocyte-heart ( 1 )

Upstream Regulation
Putative in vivo kinases:
CAMK2A (human) ( 1 )
Kinases, in vitro:
CAMK2A (human) ( 1 )

Downstream Regulation
Effects of modification on Kir6.2:
receptor internalization, induced ( 1 )

References 

1

Sierra A, et al. (2013) Regulation of Cardiac ATP-sensitive Potassium Channel Surface Expression by Calcium/Calmodulin-dependent Protein Kinase II. J Biol Chem 288, 1568-81
23223335   Curated Info