Ser245

Site Information
PsGPGPPsPTPPAPR SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 11546901

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 2 ) , immunoassay ( 1 ) , immunoprecipitation ( 2 ) , mass spectrometry ( 2 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 , 2 )

Upstream Regulation
Treatments:	dopamine ( 2 )

References
1	Peeler JC, et al. (2017) Isopeptide and ester bond ubiquitination both regulate degradation of the human dopamine receptor 4. J Biol Chem 292, 21623-21630 29101232 Curated Info
2	Spooren A, et al. (2010) Resistance of the dopamine D4 receptor to agonist-induced internalization and degradation. Cell Signal 22, 600-9 19932171 Curated Info