Thr125

Site Information
QSSVTQVtEQsPkVQ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 11537184

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 3 , 4 , 5 )
Disease tissue studied:	breast cancer ( 1 )
Relevant cell line - cell type - tissue:	HCC1937 (breast cell) ( 1 ) , HeLa (cervical) ( 4 ) , HUES-7 ('stem, embryonic') ( 5 ) , HUES-9 ('stem, embryonic') ( 3 ) , MCF-7 (breast cell) ( 1 )

References
1	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
2	Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25 22424773 Curated Info
3	Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3 21406692 Curated Info
4	Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5 21712546 Curated Info
5	Van Hoof D, et al. (2009) Phosphorylation dynamics during early differentiation of human embryonic stem cells. Cell Stem Cell 5, 214-26 19664995 Curated Info