Tyr228
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Home > Phosphorylation Site Page: > Tyr228  -  SSTR2 (mouse)

Site Information
LTIICLCyLFIIIKV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450819

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
CHO (fibroblast) [EphB1 (human), transfection] ( 1 ) , COS (fibroblast) ( 1 )

Upstream Regulation
Regulatory protein:
SSTR2 (mouse) ( 1 )
Treatments:
vapreotide ( 1 )

Downstream Regulation
Effects of modification on SSTR2:
molecular association, regulation ( 1 )
Induce interaction with:
SHP-2 (mouse) ( 1 )

References 

1

Ferjoux G, et al. (2003) Critical role of Src and SHP-2 in sst2 somatostatin receptor-mediated activation of SHP-1 and inhibition of cell proliferation. Mol Biol Cell 14, 3911-28
12972574   Curated Info

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