Lys394
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Home > Acetylation Site Page: > Lys394  -  NNT (human)

Site Information
LYSNNItkLLkAISP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 11319241
Available spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 )
Disease tissue studied:
gastric cancer ( 9 ) , lung cancer ( 1 , 2 , 3 , 4 , 5 , 6 ) , non-small cell lung cancer ( 2 , 5 , 6 , 8 , 10 ) , non-small cell lung adenocarcinoma ( 1 , 2 , 5 , 6 , 8 ) , non-small cell large cell lung carcinoma ( 2 , 6 ) , non-small cell squamous cell lung carcinoma ( 1 ) , small-cell lung cancer ( 3 , 4 )
Relevant cell line - cell type - tissue:
A549 (pulmonary) ( 5 ) , DMS53 (pulmonary) ( 4 ) , DMS79 (pulmonary) ( 3 ) , HCC15 (pulmonary) ( 1 ) , HCC78 (pulmonary) ( 2 ) , HeLa (cervical) ( 7 ) , Jurkat (T lymphocyte) ( 12 ) , liver ( 11 ) , LOU-NH91 (squamous) ( 1 ) , lung ( 1 , 2 , 3 , 4 , 5 , 6 ) , MKN-45 (gastric) ( 9 ) , NCI-H128 (pulmonary) ( 3 ) , NCI-H1299 (pulmonary) ( 6 ) , NCI-H1355 (pulmonary) ( 5 ) , NCI-H1417 (pulmonary) ( 3 ) , NCI-H1703 (squamous) ( 1 ) , NCI-H1734 (pulmonary) ( 6 ) , NCI-H1781 (pulmonary) ( 2 ) , NCI-H1792 (pulmonary) ( 5 ) , NCI-H1944 (pulmonary) ( 6 ) , NCI-H2073 (pulmonary) ( 1 ) , NCI-H209 (pulmonary) ( 3 ) , NCI-H2228 (pulmonary) ( 2 , 8 ) , NCI-H23 (pulmonary) ( 5 ) , NCI-H2342 (pulmonary) ( 1 ) , NCI-H3122 (pulmonary) ( 2 ) , NCI-H3255 (pulmonary) ( 10 ) , NCI-H358 (pulmonary) ( 6 ) , NCI-H441 (pulmonary) ( 5 ) , NCI-H446 (pulmonary) ( 4 ) , NCI-H460 (pulmonary) ( 6 ) , NCI-H524 (pulmonary) ( 3 ) , NCI-H526 (pulmonary) ( 4 ) , NCI-H661 (pulmonary) ( 2 ) , NCI-H69 (pulmonary) ( 4 ) , NCI-H82 (pulmonary) ( 4 )

References 

1

Rikova K (2013) CST Curation Set: 20218; Year: 2013; Biosample/Treatment: cell line, H2342, H2073, Lou-NH91, HCC15, H1703; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK
Curated Info

2

Rikova K (2013) CST Curation Set: 20219; Year: 2013; Biosample/Treatment: cell line, H2228, H3122, HCC78, H661, H1781; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK
Curated Info

3

Rikova K (2013) CST Curation Set: 20213; Year: 2013; Biosample/Treatment: cell line, H1417, DMS79, H128, H209, H524; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK
Curated Info

4

Rikova K (2013) CST Curation Set: 20214; Year: 2013; Biosample/Treatment: cell line, DMS53, H526, H69, H82, H446; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK
Curated Info

5

Rikova K (2013) CST Curation Set: 20215; Year: 2013; Biosample/Treatment: cell line, A549, H1355, H23, H441, H1792; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK
Curated Info

6

Rikova K (2013) CST Curation Set: 20216; Year: 2013; Biosample/Treatment: cell line, H1299, H1944, H358, H1734, H460; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK
Curated Info

7

Weinert BT, et al. (2013) Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell Rep 4, 842-51
23954790   Curated Info

8

Rikova K (2013) CST Curation Set: 18854; Year: 2013; Biosample/Treatment: cell line, H2228/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK
Curated Info

9

Rikova K (2012) CST Curation Set: 16030; Year: 2012; Biosample/Treatment: cell line, MKN45/crizotinib; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK
Curated Info

10

Rikova K (2012) CST Curation Set: 16031; Year: 2012; Biosample/Treatment: cell line, H3255/iressa; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK
Curated Info

11

Zhao S, et al. (2010) Regulation of cellular metabolism by protein lysine acetylation. Science 327, 1000-4
20167786   Curated Info

12

Choudhary C, et al. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-40
19608861   Curated Info