Ser696
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Home > Phosphorylation Site Page: > Ser696  -  Raptor (mouse)

Site Information
EKNYPLPsPAATEGG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 11315003

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , mass spectrometry ( 1 , 2 , 3 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 1 , 3 ) , 'muscle, skeletal' ( 2 )

Upstream Regulation
Treatments:
insulin ( 3 ) , mechanical stress ( 2 ) , MK-2206 ( 3 ) , rapamycin ( 2 )

Downstream Regulation
Effects of modification on Raptor:
molecular association, regulation ( 2 )
Effects of modification on biological processes:
signaling pathway regulation ( 2 )
Induce interaction with:
PRAS40 (mouse) ( 2 ) , p70S6K (mouse) ( 2 )

References 

1

Parker BL, et al. (2015) Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Sci Signal 8, rs6
26060331   Curated Info

2

Frey JW, Jacobs BL, Goodman CA, Hornberger TA (2014) A role for Raptor phosphorylation in the mechanical activation of mTOR signaling. Cell Signal 26, 313-22
24239769   Curated Info

3

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info