Ser962

Site Information
SSRsGREsVSTAsDQ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 11279402

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 6 ) , mass spectrometry ( 1 , 2 , 4 , 5 ) , mutation of modification site ( 6 ) , phospho-antibody ( 6 ) , western blotting ( 6 )
Disease tissue studied:	lung cancer ( 2 ) , non-small cell lung adenocarcinoma ( 2 )
Relevant cell line - cell type - tissue:	'neuron, hippocampal' ( 6 ) , HEK293T (epithelial) ( 6 ) , HeLa (cervical) ( 1 , 4 , 5 ) , lung ( 2 )

Upstream Regulation
Putative in vivo kinases:	AurA (human) ( 6 ) , AurB (human) ( 6 )
Kinases, in vitro:	AurA (human) ( 6 ) , AurB (human) ( 6 )

References
1	Huang H, et al. (2016) Simultaneous Enrichment of Cysteine-containing Peptides and Phosphopeptides Using a Cysteine-specific Phosphonate Adaptable Tag (CysPAT) in Combination with titanium dioxide (TiO2) Chromatography. Mol Cell Proteomics 15, 3282-3296 27281782 Curated Info
2	Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96 23911959 Curated Info
3	Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21 23312004 Curated Info
4	Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71 23186163 Curated Info
5	Nishioka T, Nakayama M, Amano M, Kaibuchi K (2012) Proteomic screening for Rho-kinase substrates by combining kinase and phosphatase inhibitors with 14-3-3ζ affinity chromatography. Cell Struct Funct 37, 39-48 22251793 Curated Info
6	Khazaei MR, Püschel AW (2009) Phosphorylation of the par polarity complex protein Par3 at serine 962 is mediated by aurora a and regulates its function in neuronal polarity. J Biol Chem 284, 33571-9 19812038 Curated Info