Ser487

Site Information
INFSRVPsQ______ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 11146876

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 )
Disease tissue studied:	leukemia ( 6 , 7 ) , acute myelogenous leukemia ( 6 , 7 ) , lung cancer ( 3 ) , non-small cell lung cancer ( 3 ) , neuroblastoma ( 1 , 4 ) , pancreatic ductal adenocarcinoma ( 2 )
Relevant cell line - cell type - tissue:	'pancreatic, ductal'-pancreas ( 2 ) , bone marrow ( 6 , 7 ) , HCC2279 (pulmonary) ( 3 ) , HCC366 (pulmonary) ( 3 ) , HCC78 (pulmonary) ( 3 ) , Jurkat (T lymphocyte) ( 5 , 8 ) , LAN-6 (neural crest) ( 1 ) , NCI-H1395 (pulmonary) ( 3 ) , NCI-H1568 (pulmonary) ( 3 ) , NCI-H2030 (pulmonary) ( 3 ) , NCI-H2172 (pulmonary) ( 3 ) , NCI-H647 (pulmonary) ( 3 ) , SH-SY5Y (neural crest) ( 1 ) , SMS-KCN-A (neural crest) ( 1 , 4 )

References
1	Palacios-Moreno J, et al. (2015) Neuroblastoma Tyrosine Kinase Signaling Networks Involve FYN and LYN in Endosomes and Lipid Rafts. PLoS Comput Biol 11, e1004130 25884760 Curated Info
2	Britton D, et al. (2014) Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets. PLoS One 9, e90948 24670416 Curated Info
3	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
4	Rikova K (2010) CST Curation Set: 9206; Year: 2010; Biosample/Treatment: cell line, SMS-KCN-A/untreated; Disease: neuroblastoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Curated Info
5	Possemato A (2010) CST Curation Set: 9047; Year: 2010; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
6	Gu T (2009) CST Curation Set: 7672; Year: 2009; Biosample/Treatment: tissue, bone marrow/untreated; Disease: acute myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Curated Info
7	Gu T (2009) CST Curation Set: 7665; Year: 2009; Biosample/Treatment: tissue, bone marrow/untreated; Disease: acute myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Curated Info
8	Possemato A (2008) CST Curation Set: 4735; Year: 2008; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Curated Info