Ser185
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Home > Phosphorylation Site Page: > Ser185  -  GIRK1 (rat)

Site Information
GCMFIKMsQPKKRAE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450683

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
oocyte [CPEB (mouse)] ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCA (rat) ( 1 )
Treatments:
calphostin_C ( 1 ) , chelerythrine ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on GIRK1:
activity, inhibited ( 1 )

References 

1

Mao J, et al. (2004) Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C. Proc Natl Acad Sci U S A 101, 1087-92
14732702   Curated Info