Ser431
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Home > Phosphorylation Site Page: > Ser431  -  CLOCK (human)

Site Information
FDHsPtPsASsRSsR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 11087834

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 )

Upstream Regulation
Regulatory protein:
BMAL1 (human) ( 1 )
Treatments:
LY294002 ( 1 )

Downstream Regulation
Effects of modification on CLOCK:
phosphorylation ( 1 ) , protein degradation ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )

References 

1

Spengler ML, Kuropatwinski KK, Schumer M, Antoch MP (2009) A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation. Cell Cycle 8, 4138-46
19946213   Curated Info

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