Ser153
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Home > Phosphorylation Site Page: > Ser153  -  KLF5 (human)

Site Information
LRTGLYKsQRPCVTH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 10945600

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 )
Disease tissue studied:
HER2 positive breast cancer ( 1 ) , luminal A breast cancer ( 1 ) , breast cancer, triple negative ( 1 ) , endometrial cancer ( 2 ) , endometrial adenocarcinoma ( 2 )
Relevant cell line - cell type - tissue:
breast ( 1 ) , HEC-1B (endometrial) ( 2 )

Downstream Regulation
Effects of modification on biological processes:
transcription, altered ( 2 )

References 

1

Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275   Curated Info

2

Zhang Z, Teng CT (2003) Phosphorylation of Kruppel-like factor 5 (KLF5/IKLF) at the CBP interaction region enhances its transactivation function. Nucleic Acids Res 31, 2196-208
12682370   Curated Info