Ser194
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Home > Phosphorylation Site Page: > Ser194  -  IGFBP3 (human)

Site Information
KVDyEsQstDtQNFs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 10902818

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
brain cancer ( 1 ) , glioblastoma ( 1 ) , glioma ( 1 ) , prostate cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CK2A1 (human) ( 1 )
Treatments:
DMAT ( 1 ) , TBB ( 1 )

Downstream Regulation
Effects of modification on IGFBP3:
phosphorylation ( 1 )
Effects of modification on biological processes:
apoptosis, altered ( 1 )

References 

1

Cobb LJ, Mehta H, Cohen P (2009) Enhancing the apoptotic potential of insulin-like growth factor-binding protein-3 in prostate cancer by modulation of CK2 phosphorylation. Mol Endocrinol 23, 1624-33
19556345   Curated Info