Lys257
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Home > Sumoylation Site Page: > Lys257  -  ataxin-7 (human)

Site Information
RIMTPSVkVEKIHPK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 10902804

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , immunoassay ( 1 ) , mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'neuron, Purkinje' ( 1 ) , brain ( 1 ) , COS7 (fibroblast) ( 1 ) , HeLa (cervical) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Janer A, et al. (2010) SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7. Hum Mol Genet 19, 181-95
19843541   Curated Info