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Site Information |
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KQAEAIMsPRFIGRR SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 448544 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
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Upstream Regulation | |
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Downstream Regulation | |
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Effects of modification on TH iso3: | |
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References | |
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Zhang X, et al. (2020) The Inhibition Effects of Shenmai Injection on Acetylcholine-Induced Catecholamine Synthesis and Secretion by Modulating Nicotinic Acetylcholine Receptor Ion Channels in Cultured Bovine Adrenal Medullary Cells. Evid Based Complement Alternat Med 2020, 8514926
33456492 Curated Info |
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Jorge-Finnigan A, et al. (2017) Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules. J Biol Chem 292, 14092-14107
28637871 Curated Info |
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DeNardo BD, et al. (2013) Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma. PLoS One 8, e82513
24349301 Curated Info |
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Gordon SL, Bobrovskaya L, Dunkley PR, Dickson PW (2009) Differential regulation of human tyrosine hydroxylase isoforms 1 and 2 in situ: Isoform 2 is not phosphorylated at Ser35. Biochim Biophys Acta 1793, 1860-7
19833152 Curated Info |
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Lehmann IT, et al. (2006) Differential regulation of the human tyrosine hydroxylase isoforms via hierarchical phosphorylation. J Biol Chem 281, 17644-51
16644734 Curated Info |
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Kobori N, et al. (2004) Enhancement of tyrosine hydroxylase phosphorylation and activity by glial cell line-derived neurotrophic factor. J Biol Chem 279, 2182-91
14570886 Curated Info |
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Toska K, et al. (2002) Regulation of tyrosine hydroxylase by stress-activated protein kinases. J Neurochem 83, 775-83
12421349 Curated Info |
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Bodeau-Péan S, et al. (1999) A human tyrosine hydroxylase isoform associated with progressive supranuclear palsy shows altered enzymatic activity. J Biol Chem 274, 3469-75
9920892 Curated Info |
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Sutherland C, et al. (1993) Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP-kinase-activated kinases 1 and 2. Eur J Biochem 217, 715-22
7901013 Curated Info |