Ser812
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Home > Phosphorylation Site Page: > Ser812  -  myocardin (mouse)

Site Information
EVLLNSHsPIGKVSD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 10791200

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
fibrosarcoma of soft tissue ( 1 )
Relevant cell line - cell type - tissue:
C3H10T1/2 (fibroblast) ( 1 ) , CHO (fibroblast) ( 1 ) , HT1080 (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
ERK1 (human) ( 1 ) , ERK2 (human) ( 1 )
Kinases, in vitro:
ERK1 (human) ( 1 ) , ERK2 (human) ( 1 )
Treatments:
phorbol_ester ( 1 ) , U0126 ( 1 )

Downstream Regulation
Effects of modification on myocardin:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
CBP (human) ( 1 )

References 

1

Taurin S, et al. (2009) Phosphorylation of myocardin by extracellular signal-regulated kinase. J Biol Chem 284, 33789-94
19776005   Curated Info

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