Tyr386
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Home > Phosphorylation Site Page: > Tyr386  -  Catalase (human)

Site Information
yRARVANyQRDGPMC   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450445

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
breast cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Abl (human) ( 1 ) , Arg (human) ( 1 )
Kinases, in vitro:
Abl (human) ( 1 ) , Arg (human) ( 1 )
Treatments:
H2O2 ( 1 ) , imatinib ( 1 )

Downstream Regulation
Effects of modification on Catalase:
enzymatic activity, induced ( 1 )

References 

1

Cao C, Leng Y, Kufe D (2003) Catalase activity is regulated by c-Abl and Arg in the oxidative stress response. J Biol Chem 278, 29667-75
12777400   Curated Info