Ser34

Site Information
TSDDIKKsYRKLALk SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 10407117

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	COS7 (fibroblast) ( 1 ) , Jurkat (T lymphocyte) ( 2 )

Upstream Regulation
Putative in vivo kinases:	PKCG (human) ( 1 )
Kinases, in vitro:	PKCG (human) ( 1 )

Downstream Regulation
Effects of modification on DNAJC5:	molecular association, regulation ( 1 )
Effects of modification on biological processes:	apoptosis, inhibited ( 1 )
Induce interaction with:	HSP70 (human) ( 1 )

References
1	Shirafuji T, et al. (2018) The Role of Cysteine String Protein α Phosphorylation at Serine 10 and 34 by Protein Kinase Cγ for Presynaptic Maintenance. J Neurosci 38, 278-290 29167402 Curated Info
2	Zhou J (2009) CST Curation Set: 5905; Year: 2009; Biosample/Treatment: cell line, Jurkat/TPA; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (K/R)XpSX(K/R)Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser) PKC Substrate Antibody Cat#: 2261, PTMScan(R) Phospho-PKC Substrate Motif (K/RXpSXK/R) Immunoaffinity Beads Cat#: 1985 Curated Info

References

Shirafuji T, et al. (2018) The Role of Cysteine String Protein α Phosphorylation at Serine 10 and 34 by Protein Kinase Cγ for Presynaptic Maintenance. J Neurosci 38, 278-290
29167402 Curated Info

Zhou J (2009) CST Curation Set: 5905; Year: 2009; Biosample/Treatment: cell line, Jurkat/TPA; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (K/R)XpSX(K/R)Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser) PKC Substrate Antibody Cat#: 2261, PTMScan(R) Phospho-PKC Substrate Motif (K/RXpSXK/R) Immunoaffinity Beads Cat#: 1985
Curated Info