Tyr340
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Home > Phosphorylation Site Page: > Tyr340  -  RAF1 (chicken)

Site Information
RGQRDssyyWEIEAS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447749

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
embryo ( 1 ) , endothelial ( 2 ) , HUVEC (endothelial) ( 2 )

Upstream Regulation
Putative in vivo kinases:
Src (chicken) ( 2 )
Treatments:
FGF2 ( 2 ) , VEGF ( 2 )

Downstream Regulation
Effects of modification on RAF1:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 2 )

References 

1

Hood JD, et al. (2003) Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. J Cell Biol 162, 933-43
12952943   Curated Info

2

Alavi A, et al. (2003) Role of Raf in vascular protection from distinct apoptotic stimuli. Science 301, 94-6
12843393   Curated Info

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