Ser289
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Home > Phosphorylation Site Page: > Ser289  -  NHERF (rabbit)

Site Information
PALARsAssDTSEEL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450313

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 , 2 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 , 2 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
GRK6 (human) ( 2 )
Kinases, in vitro:
GRK6 (human) ( 2 )
Treatments:
cAMP_analog ( 1 )

References 

1

Zizak M, et al. (1999) cAMP-induced phosphorylation and inhibition of Na(+)/H(+) exchanger 3 (NHE3) are dependent on the presence but not the phosphorylation of NHE regulatory factor. J Biol Chem 274, 24753-8
10455146   Curated Info

2

Hall RA, et al. (1999) G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction. J Biol Chem 274, 24328-34
10446210   Curated Info