Tyr83
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Home > Phosphorylation Site Page: > Tyr83  -  HCRTR1 (human)

Site Information
HMRTVTNyFIVNLSL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 10206803

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
CHO (fibroblast) ( 1 )

Upstream Regulation
Treatments:
orexin ( 1 )

Downstream Regulation
Effects of modification on HCRTR1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
apoptosis, altered ( 1 )
Induce interaction with:
SHP-2 (human) ( 1 )

References 

1

El Firar A, et al. (2009) Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis. FASEB J 23, 4069-80
19661287   Curated Info

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