Tyr1111
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Home > Phosphorylation Site Page: > Tyr1111  -  TIE2 (mouse)

Site Information
TLyEKFTyAGIDCsA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450257

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on TIE2:
enzymatic activity, inhibited ( 1 ) , phosphorylation ( 1 ) , protein conformation ( 1 )

References 

1

Sturk C, Kim H, Jones N, Dumont DJ (2010) A negative regulatory role for Y1111 on the Tie-2 RTK. Cell Signal 22, 676-83
20026268   Curated Info

2

Niu XL, Peters KG, Kontos CD (2002) Deletion of the carboxyl terminus of Tie2 enhances kinase activity, signaling, and function. Evidence for an autoinhibitory mechanism. J Biol Chem 277, 31768-73
12082108   Curated Info