Ser605
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Home > Phosphorylation Site Page: > Ser605  -  SYN1 (cow)

Site Information
AGPTRQAsQAGPMPR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450236

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 ) , peptide sequencing ( 3 ) , phosphopeptide mapping ( 3 )

Upstream Regulation
Kinases, in vitro:
CAMK2A (human) ( 1 ) , CAMK2A (rat) ( 3 ) , PAK1 (rat) ( 1 ) , PAK2 (human) ( 1 ) , PAK3 (rat) ( 1 )

References 

1

Sakurada K, et al. (2002) Synapsin I is phosphorylated at Ser603 by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin. J Biol Chem 277, 45473-9
12237306   Curated Info

2

Matsubara M, et al. (1996) Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions. J Biol Chem 271, 21108-13
8702879   Curated Info

3

Czernik AJ, Pang DT, Greengard P (1987) Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin I. Proc Natl Acad Sci U S A 84, 7518-22
3118371   Curated Info