Tyr27
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Home > Phosphorylation Site Page: > Tyr27  -  Caldesmon (chicken)

Site Information
LEAERLsyQRNDDDE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450224

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , phosphoamino acid analysis ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
EGFR (human) ( 1 )

Downstream Regulation
Effects of modification on Caldesmon:
molecular association, regulation ( 1 )
Induce interaction with:
SHC1 (human) ( 1 )

References 

1

Wang Z, Danielsen AJ, Maihle NJ, McManus MJ (1999) Tyrosine phosphorylation of caldesmon is required for binding to the Shc.Grb2 complex. J Biol Chem 274, 33807-13
10559276   Curated Info