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IDUA human	MRPLRPRAALLALLASLLAAPPVAPAEAPHLVHVDAARALWPLRRFWRSTGFCPPLPHSQADQYVLSWDQQLNLAYVGAVPHRGIKQVRTHWLLELVTTRGSTGRGLSYNFTHLDGYLDLLRENQLLPGFELMGSASGHFTDFEDKQQVFEWKDLVSsLARRYIGRYGLAHVSKWNFETWNEPDHHDFDNVSMTMQGFLNYYDACSEGLRAASPALRLGGPGDSFHTPPRSPLSWGLLRHCHDGTNFFTGEAGVRLDYISLHRKGARSSISILEQEKVVAQQIRQLFPKFADTPIYNDEADPLVGWSLPQPWRADVTYAAMVVKVIAQHQNLLLANTTSAFPYALLSNDNAFLSYHPHPFAQRTLTARFQVNNTRPPHVQLLRKPVLTAMGLLALLDEEQLWAEVSQAGTVLDSNHTVGVLASAHRPQGPADAWRAAVLIYASDDTRAHPNRSVAVTLRLRGVPPGPGLVYVTRyLDNGLCSPDGEWRRLGRPVFPTAEQFRRMRAAEDPVAAAPRPLPAGGRLTLRPALRLPSLLLVHVCARPEKPPGQVTRLRALPLTQGQLVLVWSDEHVGSKCLWTYEIQFSQDGKAYTPVSRKPSTFNLFVFSPDTGAVSGSYRVRALDYWARPGPFSDPVPYLEVPVPRGPPSPGNP
IDUA mouse	---------MLTFFAAFLAAP-LALAESPYLVRVDAARPLRPLLPFWRSTGFCPPLPHDQADQYDLSWDQQLNLAYIGAVPHSGIEQVRIHWLLDLITARKSPGQGLMYNFTHLDAFLDLLMENQLLPGFELMGSPSGYFTDFDDKQQVFEWKDLVSLLARRYIGRYGLTHVSKWNFETWNEPDHHDFDNVSMTTQGFLNYYDACSEGLRIASPTLKLGGPGDSFHPLPRSPMCWSLLGHCANGTNFFTGEVGVRLDYISLHKKGAGSSIAILEQEMAVVEQVQQLFPEFKDTPIYNDEADPLVGWSLPQPWRADVTYAALVVKVIAQHQNLLFAnSSSSMRYVLLSNDNAFLSYHPYPFSQRTLTARFQVnNTHPPHVQLLRKPVLTVMGLMALLDGEQLWAEVSKAGAVLDSnHTVGVLASTHHPEGSAAAWSTTVLIYTSDDTHAHPNHSIPVTLRLRGVPPGLDLVYIVLYLDNQLSSPYSAWQHMGQPVFPSAEQFRRMRMVEDPVAEAPRPFPARGRLTLHRKLPVPSLLLVHVCTRPLKPPGQVSRLRALPLTHGQLILVWSDERVGSKCLWTYEIQFSQKGEEYAPINRRPSTFNLFVFSPDTAVVSGSYRVRALDYWARPGPFSDPVTYLDVPAS---------
IDUA rat
	.........:*:::*::****.:*:**:*:**:*****:*:**::*************:*****:***********:*****:**:***:****:*:*:*:*:*:**:*******::****:*************:**:****:*************:***********:************************:***************:***:*:*********::****::*:**:**::********:**********:***:***:*****::*::*::****:*:*****************************:************:**::*:::*:*************:**:*************:*************:***:****:********:**:*************:*:*:*:*:**:::****:****:****:*::***********::***:::****:*:**:::*:::*:****:********::*****:****:**:*****:::*::*********:**:******:********:***:******:***************:*::*:*::*:*************::***********************:**:**::.........
Consensus	MRPLRPRAALLALLAALLAAPPLALAEAPHLVRVDAARALRPLRRFWRSTGFCPPLPHDQADQYDLSWDQQLNLAYIGAVPHRGIEQVRIHWLLDLITARGSPGRGLMYNFTHLDAFLDLLRENQLLPGFELMGSASGHFTDFDDKQQVFEWKDLVSLLARRYIGRYGLAHVSKWNFETWNEPDHHDFDNVSMTMQGFLNYYDACSEGLRAASPALRLGGPGDSFHPLPRSPLCWGLLRHCANGTNFFTGEAGVRLDYISLHRKGARSSIAILEQEKAVAQQIRQLFPEFADTPIYNDEADPLVGWSLPQPWRADVTYAALVVKVIAQHQNLLLANSSSAMRYALLSNDNAFLSYHPHPFAQRTLTARFQVNNTRPPHVQLLRKPVLTAMGLLALLDEEQLWAEVSQAGAVLDSNHTVGVLASAHRPQGPAAAWRAAVLIYASDDTRAHPNRSIAVTLRLRGVPPGLDLVYITRYLDNQLCSPDGAWRRLGRPVFPSAEQFRRMRAAEDPVAAAPRPLPARGRLTLRRALRLPSLLLVHVCARPEKPPGQVSRLRALPLTQGQLILVWSDERVGSKCLWTYEIQFSQDGEAYAPINRRPSTFNLFVFSPDTAAVSGSYRVRALDYWARPGPFSDPVPYLDVPAPRGPPSPGNP