Multiple Sequence Alignment:
TRH Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270)
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TRH human MPGPWLLLALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVG---PHKRQHPGRRE--DEASWS----------------------VDVTQHKRQHPGRRS-PWLAYAVPKRQHPGRRLADPKAQRsWEEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPLEE
TRH mouse MQGPWLMMALALIFVLTGIPKSCALLEAAQEEGAVTPDLPGLEKVQVRPERR-FLRKDLQRVRGDLGAALDS------WItKRQHPGKREEKEED-VEAEERGDLGEVGAWRPHKRQHPGRRANQDKDSWSDEGDSDWLPPSWLPDFFLDSWFSDAPQVKRQHPGRRSFPWMESDVTKRQHPGRRFIDPELQRSWEETEGEE---GGLMPEKRQHPGKRAVGHPCGPQGICGQTGLLQ-LLGDLSRGQETLAK-QTP-QLEAWVREPLEE
  *:****::****:::***:*:::*::****:*:::::::***:::::::**:.***:::**::**:*::::*......*::**********:**:.**:**::::*:**...**********:..*::***......................:*::*:*********.**::::*:********::**::******:*:**...::*************:*:******::**:***:.**:****:*::::*.*:*.:::*********
Consensus MQGPWLLLALALILNLTGIPGGRAQLEAAQQEAATAADHPGLDDFQRRPERRLFLRENIQRLRGDQGAALASQIFQSDWISKRQHPGKREEEEEDGVEAEEREDGGAVGAWRPHKRQHPGRRANQDEASWSDEGDSDWLPPSWLPDFFLDSWFSDAPQHKRQHPGRRSFPWLASAVPKRQHPGRRLADPEAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGACGQAGLLQGLLDDLSRGQEAEAKRQHPGRRAAWVREPLEE
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.