Multiple Sequence Alignment:
TRAIL Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290 )
           |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         | 
TRAIL human MAMMEVQGGPSLGQ----TCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKEDDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEkQQNISPLVRERGPQRVAAHITGTRGRsNtLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKEN---TKND---KQMVQYIYKytSYPDPILLMKsARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
TRAIL mouse MPSSGALKDLSFSQHFRMMVICIVLLQVLLQAVSVAVTYMYFTNEMKQLQDnYSKIGLACFSKTDEDFWDSTDGEILNRPCLQVKRQLYQLIEEVTLRTFQDTISTVPEKQLSTPPLPRGGRPQKVAAHITGITRRSNSALIPISKDGKTLGQKIESWESSRKGHSFLNHVLFRNGELVIEQEGLYYIYSQTYFRFQEAEDASKMVSKDKVRTKQLVQYIYKytsYPDPIVLMKSARNSCWSRDAEYGLYSIYQGGLFELKKNDRIFVSVTNEHLMDLDQEASFFGAFLIN
TRAIL rat MASTGNLKGPSFSQHFTMTVICIVLLQVLLQALTVAVTYMYFNNEVKQLQDNYSKIGLACFSKEDGDFWDSTDEGILNRPCLQVKRQLYQLIEEVTLRTFEKTISTVPEKQLSTPPLPRGRRPQRVAAHITGITRRSNLALIPISKDGKTLGQKIETWESSRRGHSFLNHVHLRNGELVIQEEGLYYIYSQTYYRFKEAKEASKTVSKDGGRIKQMVQYIYKYTSYPDPILLMKSARNSCWSREAEYGLYSIYQGGLFELKENDRIFVSVTNEHLMDLDHEASFFGA----
  *::.::::::*::*::.:::::**:::****::.*****:**:**.**:**:***:*:***:*:*.::**::*::::*:**:***:**:**:::::***::.*****:***::::**:*:::**:*******:::***.:::*:**::*:**:**::*****.*****:::::*******.::*:********:**:*:..:::.::*:..:.**:**************:***********::************:****:*************:*:*:*******::..
Consensus MASMGALKGPSFSQHFRMTVICIVLLQVLLQALCVAVTYMYFTNELKQLQDNYSKIGLACFSKEDDDFWDSTDEEILNRPCLQVKRQLYQLIEEVTLRTFEDTISTVPEKQLSTPPLPRGRRPQRVAAHITGITRRSNLALIPISKDGKTLGQKIESWESSRRGHSFLNHVHLRNGELVIQEEGLYYIYSQTYFRFQEAEDASKMVSKDDGRIKQMVQYIYKYTSYPDPILLMKSARNSCWSRDAEYGLYSIYQGGLFELKENDRIFVSVTNEHLMDLDHEASFFGAFLIN
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.