Multiple Sequence Alignment:
IL-1RB Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410  )
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IL-1RB human MLRLYVLVMGVSAFTLQPAAHTGAAR--------------SCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLtFAHEGQQYNITRSIELRIKKKKEEtIPVIIsPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASSTFSWGIVLAPLSLAFLVLGGIWMHRRCKHRTGKADGLTVLWPHHQDFQSYPK
IL-1RB mouse MFILLVLVTGVSAFTTPTVVHtGKVSESPITSEKPTVHGDNCQFRGREFKsELRLEGEPVVLRCPLAPHSDISSSSHSF-LTWSKLDSSQLIP-RDEPRMWVKGNILWILPAVQQDSGTYICtFRnASHCEQMSVELKVFKNTEASLPHVSYLQISALSTTGLLVCPDLKEFISSNADGKIQWYKGAILLDKGNKEFLSAGDPTRLLISnTSMDDAGYYRCVMTFTYNGQEYNITRNIELRVKGTTTEPIPVIISPLETIPASLGSRLIVPCKVFLGTGTSSNTIVWWLANSTFISAAYPRGRVTEGLHHQYSENDENYVEVSLIFDPVTREDLHTDFKCVASNPRSSQSLHTTVKEVSSTFSWSIALAPLSLIILVVGAIWMRRRCKRRAGKTYGLTKLRTDNQDFPSSPN
  *::*:***:******:::::***:::..............:*:****::*:*:*******:****::*:::::*:*:::.***:*:**::::*.::*:***:::::**:***:*:*****:**:****:*::**:**:**:**:*:**::**:**::***:*:******:**:::::*:******:::****:*::***::::*:**:::::::********:**:::**:*****:****:*::::*:********:**:*******::**********:::*::**:**:*:*::***:******::::****:***:**:************:*****::*::*:*:*:*****:******:*:******::**:*:***:****:*:**::***:*::::***:*:*:
Consensus MLRLLVLVMGVSAFTLQPAAHTGAARESPITSEKPTVHGDNCRFRGREFKRELRLEGEPVALRCPQAPHSDIASSSHRINLTWHKNDSARLIPGRDEPRMWAQDNALWILPALQQDSGTYICTFRNASHCDQMSIELRVFENTDAFLPHISYLQILALSTSGLLVCPDLKEFIRDNADGKIQWYKDAILLDKDNEEFLSARDPTRLLIHNTALDDAGYYRCVLTFAHNGQQYNITRNIELRIKGKKEEPIPVIISPLETIPASLGSRLIIPCKVFLGTGTPLNTILWWLANDTHIEAAYPRGRVTEGLRQQYSENNENYIEVPLIFDPVTREDLHMDFKCVAHNPRSFQSLRTTVKEASSTFSWGIALAPLSLAILVLGAIWMRRRCKRRAGKADGLTKLRPDNQDFQSSPN
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using MAFFT. Conservation and consensus calculated using von Neumann entropy from PFAAT.