Multiple Sequence Alignment:
SPACA1 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300      )
           |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |      
SPACA1 human MSPRGTGCSAGLLMTVGWLLLAGLQSARGTNVTAA---VQDAGLAHEGEGEEETE-----NNDSETAENYAPPET---EDVSNRNVVKEVEFGMCTVTCGIGVREVILTNGCPGGESKCVVRVEECRGPTDCGWGKPISESLESVRLACIHTSPLNRFKYMWKLLRQDQQSIILVNDSAILEVRKESHPLAFECDTLDNNEIVATIKFTVYTSSELQMRRSSLPATDAALIFVLTIGVIICVFIIFLLIFIIINWAAVKAFWGAKAsTPEVQSEQSSVRYKDSTSLDQLPTEMPG-EDDALSEWNE
SPACA1 mouse MRARGAGCPAGLLA-VGWLILVGLQASQASNVTSSGGGVQEPAVAREGESESESESEEEAENEGEVPESETTAEADAEEEVQNRTIVKEVEFGMCTVTCGVGIREVILTNGCPGGESKCVVRVEECRGPVDCGWGKPISENLDSARLSCVHISPENRFKYVWKLLKPDQQPVILTNDSAVLEITREIRPLAFECDTLDNNEMVASVKFTVYTTNELQMRRSSRPDTDAVLVFVLTIGVIICIFVIFVLIFIIINWAAVKSFWGSKtsAtEIQsELssMRYKDSTsLDQSPTDIPVHEDDALsEWNE
SPACA1 rat MRARGAGCPAWLLA-LGWLILVGLQASQASNVTSS---IQDPGMAREGESSSENEPEEEIENEGEVVETDTTIEA--EEEVQNKTVVKEVEFGMCTVTCGVGIREVILTNGCPGGESKCVVRVEECRGPVDCGWGRPISESLESARLSCIHISPENRFkYIWKLLKPDQQPVILINDSAVLEVPRELHPMAFECDTLDNNEMVASVKFTVYTTTELQMKRSTRPDTDAVLVFVLTIGVIICIFVIFVLIFIIINWAAVKSFWGAKAstTEIQsEMsSMRYKDSTSLDQSPTDIPVHEDDALsEWNE
  *::**:**:*:**:.:***:*:***:::::***::...:*:::.*:***:::*.*.:::.:*::*::*..:::*:..:*:*:*:::**************:*:**************************:*****:****:*:*:**:*:*:**:*****.****::***::**.****:**:.:*.:*:***********:**::******:.****:**::*:***:*:**********:*:**:************:***:*:*::*:***.**:**********:**::*::**********
Consensus MRARGAGCPAGLLA-VGWLILVGLQASQASNVTSS---VQDPGLAREGESESENEPEEEAENEGEVAENDTTAEA--EEEVQNRTVVKEVEFGMCTVTCGVGIREVILTNGCPGGESKCVVRVEECRGPVDCGWGKPISESLESARLSCIHISPENRFKYIWKLLKPDQQPVILINDSAVLEVRREIHPLAFECDTLDNNEMVASVKFTVYTTNELQMRRSSRPDTDAVLVFVLTIGVIICIFVIFVLIFIIINWAAVKSFWGAKASTTEIQSEQSSMRYKDSTSLDQSPTDIPVHEDDALSEWNE
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.