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SIRT2 human	MAEPDPSHPLETQAGKVQEAQDsDsDsEGGAAGGEADMDFLRNLFSQTLsLGSQkERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPStGLyDNLEKYHLPYPEAIFEISYFKkHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEkIFSEVTPKCEDCQSLVKP------------------------------------------------------------------------DIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFAsLIsKAPLSTPRLLINkEKAGQSDPFLGMIMGLGGGMDFDSKKAYrDVAWLGECDQGCLALAELLGWkkELEDLVRREHASIDAQsGAGVPNPsTsAsPKKsPPPAKDEARTTEREKPQ
SIRT2 iso2 human	-------------------------------------MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPkCEDCQSLVKP------------------------------------------------------------------------DIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSAsPKKSPPPAkDEARTTEREKPQ
SIRT2 mouse	MAEPDPSDPLETQAGKVQEAQDsDsDtEGGATGGEAEMDFLRNLFTQTLGLGsQkERLLDELTLEGVTRYMQSErCrKVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKk K126-ac K126-ub HPEPFFALAKELYPGQFkPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCRkEYTMGWMkEKIFSEATPRCEQCQSVVKP------------------------------------------------------------------------DIVFFGENLPSRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINkEKTGQTDPFLGMMMGLGGGMDFDSkKAYRDVAWLGDCDQGCLALADLLGWk K338-ac K338-ub kELEDLVRREHANIDAQsGsQAPNPstt T366-p T366-gl IsPGksPPPAKEAARTKEKEEQQ
SIRT2 iso2 mouse	------------------------------------MMDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRKVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCRKEYTMGWMKEKIFSEATPRCEQCQSVVKP------------------------------------------------------------------------DIVFFGENLPSRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREHANIDAQSGSQAPNPSTTIsPGKSPPPAKEAARTKEKEEQQ
SIRT2 rat	-------------------------------------MDFLRNLFTQTLGLGsQk K18-ac K18-ub ERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPsTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEkGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMsWMKEkIFSEATPkCEKCQNVVKP------------------------------------------------------------------------DIVFFGENLPPRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINkEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWk-ELEDLVRREHANIDAQSGSQASNPsATVsPRKsPPPAKEAARTKEKEEH-
SIRT2 iso2 rat	MAEPDPSDPLENQAGKVQEAQDsDsDTEGGATGGEAEMDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEKIFSEATPKCEKCQNVVKPGEPQTPFFHWPARTSNLATLLPGLSPTVLQRVGICLPFPPHPCPSWAPTPACFSSVPHVSSPLSLCLSVSTSDIVFFGENLPPRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREHANIDAQSGSQASNPSATVSPRKSPPPAKEAARTKEKEEH-
	.....................................********:***:*****************:*********:**************************:**********************************************:****:*****************:****::***************::**::**:::*********:**:**.**::***                                                                        *******:**:**********:*****::*******************:**********:**:******:**********************:*********:*****:***********:******::::***:::**.*******::***:*:*:.:
Consensus	MAEPDPS-PLE-QAGKVQEAQDSDSD-EGGA-GGEAEMDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCRKEYTMSWMKEKIFSEATPKCEDCQSVVKP------------------------------------------------------------------------DIVFFGENLPARFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREHANIDAQSGSQAPNPSTTASPRKSPPPAKEAARTKEKEEQQ