Multiple Sequence Alignment:
IL6 Download MSA
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IL6 human MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPkMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFEss-EEQARAVQMSTKVLIQFLQKKAKNLDAItTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
IL6 mouse MKFLSARDFHPVAF-LGLMLVTTTAFPTSQVRRGDFTEDT-TPNRPVYTTSQVGGLITHVLWEIVEMRKELCNGNSDCMNNDDALAENNLKLPEIQRNDGCYQTGYNQEICLLKISSGLLEYHSYLEYMKNNLKDNKKDKARVLQRDTETLIHIFNQEVKDLHKIVLPTPISNALLTDKLESQKEWLRTKTIQFILKSLEEFLKVTLRSTRQT
IL6 rat MKFLSARDFQPVAF-LGLMLLTATAFPTSQVRRGDFTEDT-THNRPVYTTSQVGGLITYVLREILEMRKELCNGNSDCMNSDDALSENNLKLPEIQRNDGCFQTGYNQEICLLKICSGLLEFRFYLEFVKNNLQDNKKDKARVIQSNTETLVHIFKQEIKDSYKIVLPTPTSNALLMEKLESQKEWLRTKTIQLILKALEEFLKVTMRSTRQT
  *:::*:::*.****.***:*::::***:::::::*:::::.::::*::::::::::*:::*.:*.::***:**::::*:::::**:****:**:::::***:*:*:*:*:**:**.:****:..***:.:*::.::::::**:.*..*::*::::.:::*::.:*::*:*::**:*..**::*::**:::*:::**::::***::::*::**:
Consensus MKFLSARDFQPVAF-LGLMLVTATAFPTSQVRRGDFTEDT-THNRPVYTTSQVGGLITYVLREILEMRKELCNGNSDCMNSDDALAENNLKLPEIQRNDGCFQTGYNQEICLLKICSGLLEFRFYLEYLKNNLQDNKKDKARVIQRNTETLIHIFNQEAKDLDKIVLPTPTSNALLLDKLESQKEWLRTKTIQLILKSLEEFLKVTLRSTRQT
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.