(        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350  )
	|         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |
MDH1 human	------------------MSEPIRVLVTGAAGQIAYSLLySIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIAtDk K73-ac K73-ub EDVAFKDLDVAILVGsMPRREGMERKDLLk K103-ac K103-ub K103-sc ANVk K107-ac K107-ub K107-sc IFk K110-m1 K110-ub sQGAALDk K118-ac K118-ub yAKKSVkVIVVGNPANTNCLTASk K142-ac K142-ub SAPSIPkENFSCLTRLDHNRAkAQIALkLGVtANDVkNVIIWGNHsstQyPDVNHAkVKLQGkEVGVyEALk K214-ac K214-ub K214-sc DDsWLkGEFVTTVQQrGAAVIkARk K239-ac K239-ub LssAMsAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKtWk K298-ac K298-ub FVEGLPINDFsREkMDLTAk K318-ub K318-sc ELtEEkEsAFEFLssA
MDH1 iso2 human	-----------------------------------------------------------------------------------------------------------MPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
MDH1 iso3 human	MRRCsYFPKDVTVFDKDDKSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
MDH1 mouse	------------------MSEPIRVLVTGAAGQIAYSLLysIGNGsVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLQDVIATDKEEIAFKDLDVAVLVGSMPRREGMERKDLLk K103-ac K103-ub ANVk K107-ac K107-sc IFk K110-ac K110-ub K110-sc sQGTALEk K118-ac K118-ub K118-sc yAKKSVkVIVVGNPANTNCLTASkSAPSIPkENFSCLTRLDHNRAkSQIALkLGVTADDVk K179-ac K179-ub NVIIWGnHssTQYPDVNHAkVKLQGk K205-ac K205-ub K205-sc EVGVyEALk K214-ac K214-ub K214-sc DDsWLk K220-ac K220-ub K220-sc GEFITTVQQrGAAVIKARKLssAMsAAKAIADHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWk K298-ac K298-ub K298-sc FVEGLPINDFsREkMDLTAk K318-ac K318-ub K318-sc ELTEEkETAFEFLssA
MDH1 rat	------------------MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLQDVIATDKEEVAFKDLDVAVLVGSMPRREGMERKDLLkANVkIFkSQGAALEkyAKKSVKVIVVGNPANTNCLTASkSAPSIPKENFSCLTRLDHNRAkSQIALKLGVTADDVkNVIIWGNHsSTQYPDVNHAKVKLQGkEVGVYEALkDDsWLkGEFITTVQQRGAAVIkARKLsSAMSAAKAISDHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWkFVEGLPINDFSREkMDLTAkELTEEKETAFEFLssA
MDH1 pig	------------------MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTSDDVKNVIIWGNHSSTQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTVQQrGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYGVPDDLLYSFPVTIKDKTWKIVEGLPINDFSREKMDLTAKELAEEKETAFEFLSSA
	:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::..::::::::.::::****:****************:**:**:***********************************************:*********::***************************:********:**********:**************************:**:****************:*******************:**:****:*********************:****:********
Consensus	------------------MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEEVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFITTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA